In Japan, a pretty mutation known as heterochromia, seems to be popular among artists. It is said that Japanese artists love to give characters with mixed genes (such as having dragon blood like the character, Yuna, in the game, “Final Fantasy”) two different colored eyes.
Having 2 different colored eyes is said to be a fetish there.
In art, a person with cat eyes may possess mystical powers. It is thought that this belief in a person with having two different colored eyes having mystical powers arose from historic claims of Alexander the Great having 2 different colors eyes and special abilities.
I think that heterochromia is one of nature’s prettiest phenomenon and like the artists’ point of view of them.